Research and publications
Our publications
Peer-reviewed research advancing the understanding of endometrial biology and reproductive health.
Featured publication, 2023
Deciphering key genes of proliferative and secretory phase using integrated transcriptomics and network analysis
Authors
Payal Gupta, Shriya Dube, Payal Priyadarshini, Shanvi Singh, Anasuya Pravallika R, Vijay Lakshmi Srivastava, Priyanka Narad, Abhishek Sengupta
Journal
Microbiology and Biotechnology Letters
Received 26 April 2023
Accepted 28 June 2023
Published 28 September 2023
Abstract
This study focuses on endometrium receptivity, aiming to identify differentially expressed genes and associated pathways during the shift from the proliferative to the secretory phase. Researchers retrieved raw data from six GEO datasets, identified 705 differentially expressed genes, and further validated 20 key genes in an additional dataset. These identified genes are considered major biomarkers for the transition between the proliferative and secretory phases.
Key highlights
- Analysed 6 GEO datasets for comprehensive gene expression profiling
- Identified 705 differentially expressed genes
- Validated 20 key biomarker genes in an independent dataset
- Revealed critical pathways for the proliferative to secretory phase transition
Keywords